Breathing pattern and respiratory mechanics in patients with amyotrophic lateral sclerosis

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Breathing pattern and respiratory mechanics in patients with amyotrophic lateral sclerosis.

The aim of this study was to evaluate the time course of breathing pattern and respiratory mechanics in patients with amyotrophic lateral sclerosis (ALS). A study was conducted on 25 out of 38 eligible ALS patients. Neurological status, arterial blood gases (ABGs), spirometry, breathing pattern (minute ventilation (V'E), tidal volume (VT), respiratory frequency (fR), duty cycle (duration of ins...

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Respiratory support in patients with amyotrophic lateral sclerosis.

To contrast the impact of pharmacologic and respiratory interventions, riluzole, the only drug documented to prolong survival in ALS, prolongs median survival by 2–3 months with no clear subjective benefits,3 whereas noninvasive ventilation (NIV) prolonged median survival by 7–12 months and improved quality of life in a randomized trial,4 and cohort studies.5,6 Several challenges remain in the ...

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Respiratory management of patients with amyotrophic lateral sclerosis

Introduction The care of patients with amyotrophic lateral sclerosis (ALS) is a very challenging but truly rewarding role for respiratory specialists. ALS is an incurable neurodegenerative disease affecting both upper and lower motor neurons, resulting in progressive skeletal muscle weakness. At onset, it generally affects predominantly either limb or bulbar muscles. Rarely, its first presentat...

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Amyotrophic Lateral Sclerosis in a Patient with Behçet’s ‎Disease

Behçet’s ‎disease is a multisystem vasculitis. Its neurological involvement mostly includes parenchymal and non-parenchymal central nervous system manifestations. Peripheral nervous system presentations are rare. A 32-yr-old male patient who fulfilled the international study group criteria for Behçet’s disease, referred to our center with walking difficulty and repeated falling downs. Neurologi...

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Respiratory muscle function in amyotrophic lateral sclerosis.

Few data exist concerning expiratory muscle function in amyotrophic lateral sclerosis (ALS). We studied 26 patients with ALS (16 with respiratory symptoms and 10 without) and measured the maximal static expiratory mouth pressure (MEP), the gastric pressure during a maximal cough (Cough Pga), and the gastric pressure after magnetic stimulation of the lower thoracic nerve roots (Tw Pga). These me...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1997

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.97.10071614